Sermorelin Peptide

Description

Sermorelin Peptide Overview

Sermorelin Peptide is a synthetic peptide corresponding to the first 29 amino acids of human growth hormone-releasing hormone (GHRH). It has been widely studied in endocrine and peptide research because it represents the biologically active N-terminal region of GHRH.

Unlike full-length GHRH, Sermorelin is a shorter 29-amino-acid peptide. Its defined sequence and well-characterized molecular properties make it useful for laboratory research involving peptide chemistry, receptor signaling, and growth-hormone-related pathways.

For researchers, accurate product identification is important. The peptide sequence, molecular formula, molecular weight, analytical purity, and batch-specific testing should be consistent with the material supplied.

«Research Use Only: Sermorelin Peptide is supplied for laboratory and scientific research purposes only. It is not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of disease.»

What Is Sermorelin Peptide?

Sermorelin is a synthetic 29-amino-acid peptide analog of growth hormone-releasing hormone (GHRH). It corresponds to residues 1–29 of human GHRH and has been investigated extensively in studies of growth hormone signaling and endocrine physiology.

Because Sermorelin represents the N-terminal portion of GHRH responsible for receptor-related activity, it is frequently used as a research compound when studying GHRH-related signaling pathways.

Research applications may include:

• Peptide chemistry
• GHRH receptor research
• Endocrine signaling studies
• Growth hormone pathway research
• Peptide structure–activity relationship studies
• Analytical characterization of synthetic peptides

Sermorelin should not be confused with full-length human GHRH, as the two materials differ in sequence length and molecular characteristics.

Molecular Formula, Molecular Weight & Sequence

The commonly reported chemical specifications for Sermorelin are:

Property  | Specification
Product name  | Sermorelin Peptide
Peptide type  | Synthetic GHRH fragment
Length  | 29 amino acids
Sequence  | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
Molecular formula  | C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular weight  | Approximately 3357.9 g/mol
CAS number  | 86168-78-7

The exact reported molecular mass can vary slightly depending on how the peptide’s chemical form is represented and calculated. Researchers should therefore compare the product specification with the analytical results on the applicable batch COA.

Why the sequence matters

Sermorelin is a defined 29-residue peptide. Providing the complete sequence on a research product page allows researchers to verify that the material they are purchasing corresponds to the intended compound.

For quality control, molecular-weight confirmation by mass spectrometry is particularly useful alongside HPLC purity analysis.

Purity

A typical research-grade specification for Sermorelin Peptide may be:

Purity: ≥98% by HPLC

The actual analytical result should always be confirmed using the batch-specific Certificate of Analysis (COA).

Depending on the testing package, documentation may include:

• HPLC purity
• Mass spectrometry
• Calculated and observed molecular mass
• Lot/batch number
• Net peptide quantity
• Testing date
• Appearance
• Storage recommendations

A professional peptide supplier should avoid presenting a generic purity percentage as though it represents every production batch. Researchers should review the COA associated with the exact lot they receive.

Appearance

Appearance: White to off-white lyophilized powder.

Lyophilization is commonly used for synthetic peptides because it provides a dry form that can be packaged and stored under controlled conditions.

Minor differences in powder texture or color can occur because of formulation and manufacturing conditions. Appearance alone cannot confirm peptide identity or purity.

For analytical verification, researchers should rely on appropriate laboratory techniques such as HPLC and mass spectrometry.

Available Vial Sizes

Sermorelin Peptide can be offered in several research quantities depending on laboratory requirements and available inventory.

Common vial sizes include:

• 2 mg
• 5 mg
• 10 mg
• 20 mg
• 50 mg

For many laboratory projects, 5 mg and 10 mg formats provide practical quantities for research and analytical work.

Larger quantities may be appropriate for laboratories requiring material for multiple experiments or repeated analytical testing.

Always display the net peptide quantity clearly on the product page and vial label.

Storage Recommendations

Proper storage is important for maintaining the quality of synthetic peptide material.

For lyophilized Sermorelin Peptide:

• Follow the temperature specified in the product’s batch documentation.
• Keep the vial tightly sealed when not in use.
• Protect the peptide from excessive moisture.
• Minimize exposure to heat and direct light.
• Avoid unnecessary temperature cycling.
• Allow a cold vial to equilibrate appropriately before opening to reduce condensation.

Controlled frozen storage is commonly used for long-term peptide storage when supported by the manufacturer’s stability information.

Important: Storage requirements can vary according to formulation, packaging, and stability data. The specific product documentation should always take priority.

Reconstitution Information

Sermorelin Peptide is supplied as a lyophilized research material. If a laboratory protocol requires reconstitution, researchers should select a suitable solvent and concentration based on the requirements of their experiment.

General laboratory considerations include:

1. Allow the sealed vial to reach an appropriate temperature before opening.
2. Use a compatible laboratory-grade solvent.
3. Introduce the solvent carefully.
4. Avoid unnecessarily vigorous agitation.
5. Allow sufficient time for the material to dissolve.
6. Minimize excessive foaming.
7. Use aliquots when appropriate to reduce repeated freeze–thaw exposure.
8. Clearly record the concentration, solvent, preparation date, and storage conditions.

There is no universal reconstitution volume that applies to every research application.

Researchers should determine the concentration required by their validated experimental protocol and calculate the appropriate solvent volume accordingly.

Intended Use — Research Use Only

Sermorelin Peptide is intended exclusively for laboratory research.

This product should not be marketed as a medicine, dietary supplement, or therapeutic treatment. A research-use-only product should not be represented as being intended to diagnose, treat, cure, or prevent any disease.

It is not intended for human or veterinary administration.

Researchers are responsible for following applicable laboratory safety procedures, institutional requirements, and local regulations concerning the handling and disposal of research chemicals.

«Research Use Only. Not for Human or Veterinary Use.»

Packaging & Shipping Information

Sermorelin Peptide should be packaged appropriately to protect the lyophilized material during transportation.

Professional research packaging may include:

• Securely sealed vial
• Product identification label
• Net peptide quantity
• Lot or batch number
• Research-use-only labeling
• Protective secondary packaging
• Batch-specific COA or analytical documentation, where applicable

Upon receiving the shipment, researchers should inspect the packaging and vial for visible damage.

The product name, vial quantity, lot number, and accompanying documentation should be checked for consistency before the material is placed into laboratory inventory.

Shipping conditions should follow the product’s validated stability requirements and applicable transportation regulations.

Frequently Asked Questions About Sermorelin Peptide

What is Sermorelin Peptide?

Sermorelin is a synthetic 29-amino-acid peptide corresponding to the N-terminal region of human growth hormone-releasing hormone (GHRH).

How many amino acids are in Sermorelin?

Sermorelin contains 29 amino-acid residues.

What is the sequence of Sermorelin?

The sequence is:

Y-A-D-A-I-F-T-N-S-Y-R-K-V-L-G-Q-L-S-A-R-K-L-L-Q-D-I-M-S-R-NH₂

What is the molecular weight of Sermorelin?

The commonly reported molecular weight is approximately 3357.9 g/mol, depending on the chemical representation used.

What is the molecular formula?

The commonly reported molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S.

What is the CAS number?

Sermorelin is commonly identified by CAS 86168-78-7.

What does Sermorelin Peptide look like?

Research-grade Sermorelin is generally supplied as a white to off-white lyophilized powder.

What purity should I look for?

A research-grade specification may state ≥98% purity by HPLC. The actual purity should be verified against the COA for the specific batch.

Does Sermorelin come with a COA?

A professionally documented research product should provide appropriate batch-specific analytical documentation where available. Researchers should check the lot number, HPLC purity, molecular-weight data, and other available testing information.

How should Sermorelin be stored?

Follow the storage instructions provided for the specific batch. Lyophilized peptide should generally be protected from moisture, excessive heat, light, and unnecessary temperature cycling.

How is Sermorelin reconstituted?

Reconstitution depends on the laboratory protocol, desired concentration, solvent compatibility, and intended research application. There is no single volume suitable for every experiment.

Is Sermorelin the same as human growth hormone?

No. Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of GHRH. It is chemically different from human growth hormone (GH).

Is Sermorelin intended for human use?

This product is presented as a research-use-only peptide. It should not be represented as an approved human therapeutic or recommended for human or veterinary administration.

Key Takeaway

Sermorelin Peptide is a synthetic 29-amino-acid peptide corresponding to the N-terminal region of human GHRH. Its defined sequence, molecular characteristics, and research history make it a useful material for laboratory investigations involving peptide chemistry and GHRH-related signaling.

For researchers, the most important factors are accurate chemical identity, verified purity, batch-specific analytical documentation, proper storage, and transparent research-use labeling.

When purchasing Sermorelin Peptide, researchers should compare the product’s stated sequence and molecular weight with the analytical information supplied for the exact batch. This provides a more reliable basis for research than relying on appearance or generic product claims alone.

Research Use Only. Not for Human or Veterinary Use.

Continue Learning: If you found this guide helpful, you may also want to read our previous peptide education articles covering peptide concentration calculations, peptide storage, and common reconstitution mistakes to improve accuracy and maintain peptide stability during research.

Read this Helpful Topics Below To Boost Your Knowledge On Peptides

• Peptide Bubbles after reconstitution?
• Are peptides legal?
• Are peptides safe?
• How Are Peptides Made?
• What Does HPLC Testing Mean?
• How do I read a COA?
• How Should Peptides Be Stored?
• How Long Do Peptides Last?
• What’s Peptide Reconstitution?

Scientific Reference: For additional peer-reviewed information on peptide stability, sterile preparation, and pharmaceutical reconstitution practices, visit PubMed