Tesamorelin Peptide

Description

Tesamorelin Peptide Overview

Tesamorelin Peptide is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). It has been studied for its interaction with the GHRH receptor and its effects on growth-hormone-related signaling.

Tesamorelin is structurally based on human GHRH and contains a modified 44-amino-acid sequence designed to improve peptide stability. Its defined molecular structure makes it relevant to laboratory research involving peptide chemistry, receptor signaling, endocrine pathways, and structure–activity relationships.

For researchers, accurate identification is essential. The peptide sequence, molecular formula, molecular weight, analytical purity, and batch-specific testing should correspond to the actual material supplied.

«Research Use Only: Tesamorelin Peptide is supplied for laboratory and scientific research purposes only. It is not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of disease.»

What Is Tesamorelin Peptide?

Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH). It was developed by modifying the GHRH structure to improve stability while retaining interaction with the GHRH receptor.

The peptide is particularly relevant to research examining the GHRH–growth hormone–IGF-1 signaling axis.

Tesamorelin research may involve:

• Peptide chemistry
• GHRH receptor studies
• Endocrine signaling
• Growth hormone pathway research
• Peptide stability investigations
• Structure–activity relationship studies
• Analytical characterization

Tesamorelin should not be confused with sermorelin. Although both are related to GHRH, they are chemically different peptides with different sequences and molecular characteristics.

Molecular Formula, Molecular Weight & Sequence

Tesamorelin is a relatively large synthetic peptide. Its commonly reported chemical specifications include:

Property  | Specification
Product name  | Tesamorelin Peptide
Peptide type  | Synthetic GHRH analog
Length  | 44 amino acids
Sequence  | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Arg-Asn-Arg-Gln-Gly-Asp-Arg-Pro-Arg-Lys-Val
Molecular formula  | C₂₂₁H₃₃₆N₅₀O₆₈
Molecular weight  | Approximately 5135.9 g/mol
CAS number  | 373346-99-5

Tesamorelin has a modified structure compared with native human GHRH, including a C-terminal modification that contributes to its stability and pharmacological properties.

Why molecular identity matters

Researchers should verify the exact chemical form of the material they purchase. The stated sequence and molecular weight should correspond with available analytical documentation, particularly mass spectrometry.

For research-grade peptide materials, HPLC and mass spectrometry provide complementary information: HPLC is commonly used to assess chromatographic purity, while mass spectrometry helps confirm molecular identity.

Purity

A suitable research-grade specification for Tesamorelin Peptide may be:

Purity: ≥98% by HPLC

The actual purity should be confirmed using the batch-specific Certificate of Analysis (COA).

Depending on the testing package, documentation may include:

• HPLC chromatogram
• HPLC purity percentage
• Mass spectrometry results
• Calculated molecular mass
• Observed molecular mass
• Lot/batch number
• Testing date
• Net peptide quantity

Researchers should always use the analytical result for the specific lot rather than assuming that a general product-page purity statement applies identically to every batch.

Appearance

Appearance: White to off-white lyophilized powder.

Tesamorelin Peptide may be supplied as a lyophilized material to provide a dry form suitable for controlled laboratory storage.

Minor variations in color or powder texture may occur between batches because of manufacturing and drying conditions.

However, appearance alone cannot confirm identity, purity, or peptide integrity. Appropriate analytical testing should be used when those characteristics need to be verified.

5. Available Vial Sizes

Tesamorelin Peptide can be offered in several research quantities depending on laboratory requirements and available inventory.

Common research vial sizes include:

• 2 mg
• 5 mg
• 10 mg
• 20 mg
• 50 mg

For many research applications, 5 mg and 10 mg formats are practical options for individual laboratory projects.

Larger quantities may be useful for laboratories performing repeated analytical or experimental work.

The product page should clearly state the net peptide quantity per vial and avoid confusing vial size with peptide quantity.

Storage Recommendations

Appropriate storage is important for maintaining synthetic peptide quality.

For lyophilized Tesamorelin Peptide:

• Follow the storage temperature specified in the applicable product documentation.
• Keep the vial tightly sealed.
• Protect the material from moisture.
• Minimize exposure to excessive heat and direct light.
• Avoid unnecessary temperature cycling.
• Allow a cold vial to equilibrate appropriately before opening to reduce condensation.

Controlled frozen storage may be appropriate for long-term research storage when supported by the manufacturer’s stability information.

Important: Exact storage conditions can vary depending on formulation, packaging, and stability data. Always prioritize the storage instructions supplied with the specific batch.

Reconstitution Information

Tesamorelin Peptide is supplied as a lyophilized research material. When a laboratory protocol requires reconstitution, researchers should select a compatible solvent and concentration according to the intended experiment.

General laboratory considerations include:

1. Allow the sealed vial to reach an appropriate temperature before opening.
2. Use a compatible laboratory-grade solvent.
3. Introduce the solvent carefully.
4. Avoid unnecessarily vigorous agitation.
5. Allow adequate time for the peptide to dissolve.
6. Minimize excessive foaming.
7. Consider aliquoting when appropriate to limit repeated freeze–thaw exposure.
8. Record the solvent, concentration, preparation date, and storage conditions.

There is no universal reconstitution volume for Tesamorelin. The appropriate volume depends on the concentration required by the research protocol.

Researchers should calculate the required volume from the desired experimental concentration rather than using a generic volume that may not match their application.

Intended Use — Research Use Only

Tesamorelin Peptide is intended exclusively for laboratory research.

This product should not be represented as a dietary supplement, cosmetic product, or general-purpose therapeutic.

It should not be marketed for human or veterinary administration. Researchers are responsible for following applicable institutional procedures, laboratory safety requirements, and regulatory obligations.

«Research Use Only. Not for Human or Veterinary Use.»

Packaging & Shipping Information

Tesamorelin Peptide should be packaged appropriately to protect the lyophilized material during transportation.

Professional research packaging may include:

• Securely sealed vial
• Product identification label
• Net peptide quantity
• Lot/batch number
• Research-use-only statement
• Protective secondary packaging
• Batch-specific COA or analytical documentation, where applicable

Upon receipt, researchers should inspect the vial and packaging for visible damage.

The product name, quantity, lot number, and accompanying documentation should be checked for consistency before the material is placed into laboratory inventory.

Shipping conditions should follow the product’s validated stability requirements and applicable transportation regulations.

Frequently Asked Questions About Tesamorelin Peptide

What is Tesamorelin Peptide?

Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH) that has been studied in research involving GHRH receptor signaling and the growth hormone pathway.

How many amino acids are in Tesamorelin?

Tesamorelin is a 44-amino-acid peptide.

What is the sequence of Tesamorelin?

The commonly reported sequence is:

Y-A-D-A-I-F-T-N-S-Y-R-K-V-L-G-Q-L-S-A-R-K-L-L-Q-D-I-M-S-R-Q-Q-G-E-R-N-R-Q-G-D-R-P-R-K-V

The exact chemical form should be confirmed against the specification and analytical documentation for the supplied material.

What is the molecular weight of Tesamorelin?

The commonly reported molecular weight is approximately 5135.9 g/mol, although the precise value can depend on the chemical form and calculation method.

What is the molecular formula?

The commonly reported molecular formula is C₂₂₁H₃₃₆N₅₀O₆₈.

What is the CAS number?

Tesamorelin is commonly identified by CAS 373346-99-5.

What does Tesamorelin Peptide look like?

Research-grade Tesamorelin is generally supplied as a white to off-white lyophilized powder.

What purity should researchers look for?

A research-grade specification may state ≥98% purity by HPLC. Researchers should verify the actual result on the COA for their specific batch.

Should Tesamorelin come with a COA?

For professional research supply, batch-specific analytical documentation is highly valuable. Researchers should look for HPLC purity, mass-spectrometry information, lot number, molecular-weight data, and testing date where available.

How should Tesamorelin be stored?

Follow the storage conditions provided with the specific batch. Lyophilized peptide should be protected from moisture, excessive heat, direct light, and unnecessary temperature cycling.

How is Tesamorelin reconstituted?

Reconstitution depends on the research protocol, solvent compatibility, desired concentration, and experimental requirements. There is no single reconstitution volume appropriate for every laboratory application.

Is Tesamorelin the same as Sermorelin?

No. Both are related to GHRH research, but they are chemically different peptides. Tesamorelin is a longer 44-amino-acid analog, while Sermorelin corresponds to a shorter 29-amino-acid portion of GHRH.

Is Tesamorelin intended for human use?

This product description presents Tesamorelin as a research-use-only material. It should not be represented as being intended for human or veterinary administration.

Key Takeaway

Tesamorelin Peptide is a synthetic GHRH analog used in laboratory research involving peptide chemistry, GHRH receptor signaling, and endocrine pathways.

Its relatively long 44-amino-acid sequence makes accurate analytical characterization particularly important. Researchers should verify the sequence, molecular identity, HPLC purity, mass-spectrometry results, batch number, and COA before using a particular lot.

A professional product page should provide transparent specifications without making unsupported therapeutic claims. Clear research-use labeling, appropriate storage information, and reliable batch documentation help researchers make informed decisions about the material they purchase.

Research Use Only. Not for Human or Veterinary Use.

Continue Learning: If you found this guide helpful, you may also want to read our previous peptide education articles covering the following topics

• Which Peptides Are Beginners Using? 
• What Bacteriostatic Water Should I Use For My Peptide?
• What’s Peptide Reconstitution?
• How Should Peptides Be Stored?
• Peptide Bubbles after reconstitution?
• How Long Do Peptides Last?
• Discover the most in demand peptides today in 2026

Scientific Reference: For additional peer-reviewed information on peptide stability, sterile preparation, and pharmaceutical reconstitution practices, visit PubMed