Description
Epithalon Peptide Overview
Epithalon Peptide is a synthetic tetrapeptide also known as Epitalon or Epithalone. It is a short peptide consisting of four amino-acid residues and has been investigated in laboratory research involving cellular biology, gene expression, peptide chemistry, and biological aging-related pathways.
Epithalon is particularly interesting to researchers because of experimental research examining its potential relationship with telomerase activity and telomere biology. However, findings from experimental studies should not be interpreted as evidence that research-grade Epithalon is an approved anti-aging treatment or medical therapy.
Research Use Only: Epithalon Peptide is supplied for laboratory and scientific research purposes only. It is not intended for human or veterinary administration, diagnosis, treatment, cure, or prevention of disease.
What Is Epithalon Peptide?
Epithalon is a synthetic tetrapeptide composed of four amino acids. It was developed as a synthetic analogue of a peptide associated with the epithalamus and has subsequently been investigated in various experimental models.
Its short structure makes Epithalon relatively straightforward to characterize compared with larger peptide molecules.
Research involving Epithalon has explored areas such as:
- Peptide biochemistry
- Cellular biology
- Gene-expression research
- Telomere and telomerase research
- Oxidative-stress research
- Cellular aging-related pathways
- Molecular biology
- Peptide structure and function
The scientific literature surrounding Epithalon includes experimental and preclinical work, but researchers should distinguish experimental findings from established clinical evidence.
Molecular Formula, Molecular Weight & Sequence
Epithalon is a defined tetrapeptide.
| Property | Specification |
|---|---|
| Product name | Epithalon Peptide |
| Alternative names | Epitalon, Epithalone |
| Peptide length | 4 amino acids |
| Sequence | Ala-Glu-Asp-Gly (AEDG) |
| One-letter sequence | AEDG |
| Molecular formula | C₁₄H₂₂N₄O₉ |
| Molecular weight | Approximately 390.35 g/mol |
| Peptide type | Synthetic tetrapeptide |
Understanding the sequence
The four residues are:
- Ala — Alanine
- Glu — Glutamic acid
- Asp — Aspartic acid
- Gly — Glycine
Therefore, the standard sequence is:
AEDG
Because Epithalon is a small, defined peptide, its identity can be investigated using appropriate analytical techniques such as chromatography and mass spectrometry.
For research purchasing, the calculated molecular weight should be compared with the observed mass reported by the laboratory or COA, where available.
Purity
A commonly requested research specification is:
Purity: ≥98% by HPLC
However, the purity displayed on your product page should always correspond to the actual batch being supplied.
A professional Certificate of Analysis may include:
- HPLC purity percentage
- HPLC chromatogram
- Mass spectrometry
- Expected molecular weight
- Observed molecular weight
- Lot/batch number
- Testing date
- Peptide content
For maximum transparency, researchers should be encouraged to review the batch-specific COA rather than relying solely on a general product-page specification.
Appearance
Typical appearance: White to off-white lyophilized powder.
Epithalon may be supplied as a dry, lyophilized research material.
The exact appearance can vary slightly depending on manufacturing and lyophilization conditions.
Visual appearance alone cannot establish peptide identity or purity. Analytical testing such as HPLC and mass spectrometry provides substantially more useful information for research quality assessment.
5. Available Vial Sizes
Epithalon Peptide can be offered in several research quantities depending on your inventory and laboratory customers’ requirements.
Common research formats include:
- 5 mg
- 10 mg
- 20 mg
- 50 mg
- 100 mg
For a product catalog, 10 mg and 20 mg can be positioned as practical research quantities, while larger formats may suit laboratories conducting repeated analytical or experimental work.
Only advertise vial sizes that you actually stock and can support with appropriate documentation.
Storage Recommendations
Proper storage is important for maintaining the quality of lyophilized Epithalon.
General laboratory considerations include:
- Keep the vial tightly sealed.
- Protect the material from moisture.
- Minimize unnecessary exposure to heat.
- Protect from excessive direct light.
- Avoid repeated temperature fluctuations.
- Follow the manufacturer’s documented storage requirements.
- Allow cold material to equilibrate appropriately before opening to minimize condensation.
For long-term storage, researchers should follow the stability information supplied for the specific batch and formulation.
After reconstitution, stability can differ considerably from that of the original lyophilized material, so researchers should establish handling and storage conditions appropriate for their experimental protocol.
Reconstitution Information
Epithalon is commonly supplied as a lyophilized peptide.
Reconstitution should be performed according to the laboratory’s validated protocol and the specific requirements of the experiment.
General laboratory considerations include:
- Allow the sealed vial to equilibrate appropriately before opening.
- Select a solvent compatible with the intended research application.
- Introduce the solvent carefully.
- Avoid unnecessarily vigorous shaking or agitation.
- Allow adequate time for the material to dissolve.
- Record the solvent, concentration, and preparation date.
- Minimize unnecessary freeze–thaw cycles.
- Follow the applicable post-reconstitution stability protocol.
There is no single reconstitution volume appropriate for every Epithalon experiment. Researchers should determine the appropriate concentration and preparation conditions based on their experimental design and validated laboratory procedures.
Intended Use — Research Only
Epithalon Peptide is intended for laboratory and scientific research.
Potential research areas include:
- Peptide chemistry
- Molecular biology
- Cellular biology
- Telomere research
- Telomerase-related research
- Gene-expression studies
- Oxidative-stress research
- Cellular aging-related research
Epithalon should not be marketed on a research product page as:
- An anti-aging treatment
- A longevity therapy
- A disease treatment
- A prescription medicine
- A supplement
- A guaranteed method of extending lifespan
Research Use Only. Not for Human or Veterinary Administration.
Researchers are responsible for ensuring their use of the material complies with applicable laws, institutional requirements, and laboratory safety procedures.
Packaging & Shipping Information
Professional packaging helps protect the lyophilized material during transportation and provides researchers with essential identification information.
Packaging may include:
- Securely sealed vial
- Product name
- Net quantity
- Lot/batch number
- Research-use statement
- Protective secondary packaging
- Batch-specific COA or analytical documentation
When the product arrives, researchers should inspect the package and vial for visible damage.
Before placing the material into laboratory inventory, verify:
Product name + quantity + lot number + formulation + COA
Shipping conditions should be selected according to the product’s documented stability requirements and applicable transportation regulations.
Frequently Asked Questions About Epithalon Peptide
What is Epithalon Peptide?
Epithalon is a synthetic tetrapeptide consisting of four amino acids and is also known as Epitalon or Epithalone.
What is the sequence of Epithalon?
The standard sequence is:
Ala-Glu-Asp-Gly (AEDG)
How many amino acids does Epithalon contain?
Epithalon contains four amino-acid residues, making it a tetrapeptide.
What is the molecular formula?
The commonly reported molecular formula is:
C₁₄H₂₂N₄O₉
What is the molecular weight?
The molecular weight is approximately:
390.35 g/mol
What is Epithalon researched for?
Experimental research has investigated Epithalon in areas including cellular biology, gene expression, telomere-related research, telomerase pathways, and oxidative-stress biology.
What purity should researchers look for?
A research-grade Epithalon product may specify ≥98% purity by HPLC. The actual purity should be verified using the COA for the specific lot.
What does Epithalon look like?
It is typically supplied as a white to off-white lyophilized powder.
Should Epithalon come with a COA?
For professional research supply, a batch-specific COA is strongly preferable. It can provide information such as HPLC purity, mass spectrometry, molecular-weight confirmation, lot number, and testing date.
How should Epithalon be stored?
Follow the manufacturer’s storage specifications for the particular batch. Protect the lyophilized peptide from moisture, excessive heat, unnecessary light exposure, and repeated temperature fluctuations.
How is Epithalon reconstituted?
Reconstitution depends on the research application and laboratory protocol. There is no universal reconstitution volume suitable for every experiment.
Is Epithalon an anti-aging treatment?
Epithalon has been investigated experimentally in aging-related biological research, but a research-grade product should not be represented as an approved anti-aging treatment or longevity therapy.
Is Epithalon intended for human use?
No. A research-grade Epithalon product should be clearly labeled Research Use Only — Not for Human or Veterinary Administration.
Key Takeaway
Epithalon Peptide is a small, defined synthetic tetrapeptide with the sequence AEDG. Its simple molecular structure makes it a useful material for laboratory investigations involving peptide chemistry and biological research.
Key specifications
- Sequence: Ala-Glu-Asp-Gly (AEDG)
- Molecular formula: C₁₄H₂₂N₄O₉
- Molecular weight: approximately 390.35 g/mol
- Purity: ≥98% by HPLC, when supported by the applicable batch COA
- Appearance: White to off-white lyophilized powder
- Format: Research-grade peptide
- Intended use: Laboratory research only
For researchers, the most important purchasing considerations are accurate identity, documented purity, reliable analytical testing, proper storage information, and a batch-specific COA.
Research Use Only. Not for Human or Veterinary Administration.
Continue Learning: If you found this guide helpful, you may also want to read our previous peptide education articles covering the following topics
- Which Peptides Are Beginners Using?
- What Bacteriostatic Water Should I Use For My Peptide?
- What’s Peptide Reconstitution?
- How Should Peptides Be Stored?
- How do I read a COA?
- Peptide Purity explained in depth
- Peptide Bubbles after reconstitution?
- Which peptide suppresses appetite the most?
Scientific Reference: For additional peer-reviewed information on peptide stability, sterile preparation, and pharmaceutical reconstitution practices, visit
International Journal of Pharmaceutics
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