GHRP-2 Peptide

Description

GHRP-2 Peptide Overview

GHRP-2 Peptide is a synthetic growth hormone-releasing peptide (GHRP) that has been studied in laboratory research involving growth hormone secretion, ghrelin-receptor signaling, peptide pharmacology, and endocrine pathways.

GHRP-2 is also known as pralmorelin and is a synthetic hexapeptide. It acts as an agonist at the growth hormone secretagogue receptor (GHSR), making it a useful research compound for investigating pathways involved in growth hormone regulation.

For researchers, accurate chemical identity is essential. The peptide sequence, molecular formula, molecular weight, analytical purity, and batch-specific testing should correspond to the actual material supplied.

«Research Use Only: GHRP-2 Peptide is supplied for laboratory and scientific research purposes only. It is not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of disease.»

What Is GHRP-2 Peptide?

GHRP-2, or growth hormone-releasing peptide-2, is a synthetic six-amino-acid peptide belonging to the growth hormone secretagogue family.

Research has shown that GHRP-2 interacts with the growth hormone secretagogue receptor (GHSR), also known as the ghrelin receptor. This makes it useful for laboratory investigations of receptor activation and growth-hormone-related signaling.

GHRP-2 research may involve:

• Growth hormone secretagogue research
• GHSR/ghrelin receptor studies
• Endocrine signaling
• Peptide pharmacology
• Receptor-binding research
• Synthetic peptide characterization
• Structure–activity relationship studies

GHRP-2 is chemically different from GHRP-6, Ipamorelin, Sermorelin, and other growth-hormone-related peptides. Researchers should verify the exact sequence and molecular identity when selecting a research material.

Molecular Formula, Molecular Weight & Sequence

The commonly reported chemical specifications for GHRP-2 are:

Property  | Specification
Product name  | GHRP-2 Peptide
Alternative name  | Pralmorelin
Peptide type  | Synthetic hexapeptide
Sequence  | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
Peptide length | 6 residues
Molecular formula  | C₄₆H₅₆N₁₂O₆
Molecular weight  | Approximately 873.0 g/mol
CAS number  | 158861-67-7

The sequence contains several modified amino-acid residues, including D-2-naphthylalanine (D-2-Nal) and D-phenylalanine. These modifications are part of the chemical structure that distinguishes GHRP-2 from many other peptide secretagogues.

For research-grade materials, the stated molecular mass should be compared with the observed mass from appropriate analytical testing, such as mass spectrometry.

Purity

A typical research-grade specification for GHRP-2 Peptide may be:

Purity: ≥98% by HPLC

The actual purity should be confirmed using the batch-specific Certificate of Analysis (COA).

Depending on the available testing package, documentation may include:

• HPLC purity
• HPLC chromatogram
• Mass spectrometry
• Calculated molecular weight
• Observed molecular weight
• Lot/batch number
• Testing date
• Net peptide quantity

Researchers should evaluate the documentation for the exact lot they receive rather than relying only on a general product-page specification.

Appearance

Appearance: White to off-white lyophilized powder.

Lyophilization provides a dry form of the synthetic peptide that can be packaged for controlled laboratory storage.

Slight differences in powder texture or color can occur between batches because of formulation and manufacturing conditions.

Visual appearance alone should never be treated as confirmation of peptide identity or purity. Analytical techniques such as HPLC and mass spectrometry provide more meaningful information.

Available Vial Sizes

GHRP-2 Peptide can be supplied in several quantities depending on laboratory requirements and available inventory.

Common research vial sizes include:

• 2 mg
• 5 mg
• 10 mg
• 20 mg
• 50 mg

For many individual research projects, 5 mg and 10 mg formats are practical options.

Larger quantities may be suitable for laboratories conducting repeated analytical experiments or multiple research projects.

The product listing should clearly identify the net peptide quantity per vial.

Storage Recommendations

Proper storage is important for maintaining peptide quality.

For lyophilized GHRP-2 Peptide:

• Follow the storage temperature specified in the product documentation.
• Keep the vial tightly sealed when not in use.
• Protect the material from moisture.
• Minimize unnecessary exposure to heat and direct light.
• Avoid repeated temperature cycling.
• Allow a cold vial to equilibrate appropriately before opening to reduce condensation.

Controlled frozen storage may be appropriate for long-term storage when supported by the manufacturer’s stability information.

Important: Storage requirements can vary according to formulation, packaging, and stability data. The storage instructions provided with the specific batch should take priority.

Reconstitution Information

GHRP-2 Peptide is supplied as a lyophilized research material. When reconstitution is required for a laboratory experiment, researchers should select a compatible solvent and concentration based on the requirements of their validated protocol.

General laboratory considerations include:

1. Allow the sealed vial to reach a suitable temperature before opening.
2. Use an appropriate laboratory-grade solvent.
3. Introduce the solvent carefully.
4. Avoid unnecessarily vigorous agitation.
5. Allow sufficient time for the peptide to dissolve.
6. Minimize excessive foaming.
7. Consider aliquoting when appropriate to reduce repeated freeze–thaw exposure.
8. Record the solvent, concentration, preparation date, and storage conditions.

There is no universal reconstitution volume that applies to every research experiment.

The appropriate volume should be calculated from the concentration required by the laboratory protocol.

Intended Use — Research Use Only

GHRP-2 Peptide is intended exclusively for laboratory research.

It should not be represented as a dietary supplement, general wellness product, or approved therapeutic.

This research material is not intended for human or veterinary administration.

Researchers are responsible for following applicable laboratory safety procedures, institutional policies, and regulatory requirements for handling and disposal.

«Research Use Only. Not for Human or Veterinary Use.»

Packaging & Shipping Information

GHRP-2 Peptide should be packaged to protect the lyophilized material during normal transportation.

Professional research packaging may include:

• Securely sealed peptide vial
• Product identification label
• Net peptide quantity
• Lot/batch number
• Research-use-only statement
• Protective secondary packaging
• Batch-specific COA or analytical documentation, where applicable

When the shipment arrives, researchers should inspect the packaging and vial for visible damage.

The product name, quantity, lot number, and accompanying documentation should be checked for consistency before the material is entered into laboratory inventory.

Shipping conditions should follow the product’s validated stability requirements and applicable transportation regulations.

Frequently Asked Questions About GHRP-2 Peptide

What is GHRP-2 Peptide?

GHRP-2 is a synthetic hexapeptide growth hormone secretagogue that has been investigated for its interaction with the growth hormone secretagogue receptor (GHSR).

What is another name for GHRP-2?

GHRP-2 is also known as pralmorelin.

What is the sequence of GHRP-2?

The commonly reported sequence is:

D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂

How many amino acids are in GHRP-2?

GHRP-2 is a hexapeptide, meaning it contains six amino-acid residues.

What is the molecular formula of GHRP-2?

The commonly reported molecular formula is:

C₄₆H₅₆N₁₂O₆

What is the molecular weight of GHRP-2?

The molecular weight is approximately 873.0 g/mol.

What is the CAS number?

GHRP-2 is commonly identified by CAS 158861-67-7.

What does GHRP-2 Peptide look like?

Research-grade GHRP-2 is generally supplied as a white to off-white lyophilized powder.

What purity should researchers look for?

A research-grade specification may state ≥98% purity by HPLC. The actual purity should be confirmed using the COA for the specific batch.

Should GHRP-2 come with a COA?

For professional research supply, batch-specific documentation is highly valuable. Researchers should look for HPLC purity, mass-spectrometry information, lot number, molecular-weight data, and testing date where available.

How should GHRP-2 be stored?

Follow the storage conditions provided with the specific batch. Protect lyophilized peptide from moisture, excessive heat, direct light, and unnecessary temperature cycling.

How is GHRP-2 reconstituted?

Reconstitution depends on the research protocol, solvent compatibility, desired concentration, and experimental requirements. There is no single reconstitution volume suitable for every laboratory application.

Is GHRP-2 the same as GHRP-6?

No. GHRP-2 and GHRP-6 are different synthetic peptides with different sequences and molecular characteristics.

Is GHRP-2 the same as Ipamorelin?

No. Both belong to the growth hormone secretagogue research category, but they are structurally different peptides with different sequences and pharmacological profiles.

Is GHRP-2 intended for human use?

This product is presented as a research-use-only peptide and should not be marketed or recommended for human or veterinary administration.

Key Takeaway

GHRP-2 Peptide is a synthetic six-amino-acid growth hormone secretagogue that has been studied extensively in research involving GHSR signaling, peptide pharmacology, and endocrine pathways.

Its commonly reported sequence is D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂, with a molecular formula of C₄₆H₅₆N₁₂O₆ and molecular weight of approximately 873.0 g/mol.

For researchers, the most important purchasing considerations are chemical identity, analytical purity, batch-specific documentation, appropriate storage, and clear research-use labeling.

A professional GHRP-2 product page should provide enough information for researchers to compare the stated specifications with their batch-specific COA and analytical results.

Research Use Only. Not for Human or Veterinary Use.

Continue Learning: If you found this guide helpful, you may also want to read our previous peptide education articles covering the following

• What Bacteriostatic Water Should I Use For My Peptide?
• What’s Peptide Reconstitution?
• How Long Do Peptides Last?
• How Should Peptides Be Stored?
• Are peptides safe?
• Peptide Bubbles after reconstitution?

Scientific Reference: For additional peer-reviewed information on peptide stability, sterile preparation, and pharmaceutical reconstitution practices, visit PubMed